Accurate Silent Synapse Estimation from Simulator-Corrected Electrophysiological Data Using the SilentMLE Python Package
Summary: The proportion of silent (AMPAR-lacking) synapses is thought to be related to the plasticity potential of neural networks. We created a maximum-likelihood estimator of silent synapse fraction based on simulations of the underlying experimental methodology. Here, we provide a set of guidelin...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
|
Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166720301635 |