Maternal 5mCpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues

Maternal 5mCpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues

A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5mC) of alleles at CpG islands (CGIs) in their promoter regions. This 5mCpG asymmetry between the parental alleles creates allele-specific imprinted differentially methylat...

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Main Authors: Graziela de Sá Machado Araújo, Ronaldo da Silva Francisco Junior, Cristina dos Santos Ferreira, Pedro Thyago Mozer Rodrigues, Douglas Terra Machado, Thais Louvain de Souza, Jozimara Teixeira de Souza, Cleiton Figueiredo Osorio da Silva, Antônio Francisco Alves da Silva, Claudia Caixeta Franco Andrade, Alan Tardin da Silva, Victor Ramos, Ana Beatriz Garcia, Filipe Brum Machado, Enrique Medina-Acosta
格式: Article
語言:English
出版: Frontiers Media S.A. 2018-03-01
叢編:Frontiers in Genetics
主題:
PARD6G-AS1
GCSAML
GRB10
ZNF124
OR2L13
LOC284240
在線閱讀:http://journal.frontiersin.org/article/10.3389/fgene.2018.00036/full

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http://journal.frontiersin.org/article/10.3389/fgene.2018.00036/full

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