Maternal 5mCpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues
A hallmark of imprinted genes in mammals is the occurrence of parent-of-origin-dependent asymmetry of DNA cytosine methylation (5mC) of alleles at CpG islands (CGIs) in their promoter regions. This 5mCpG asymmetry between the parental alleles creates allele-specific imprinted differentially methylat...
Автори: | , , , , , , , , , , , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Frontiers Media S.A.
2018-03-01
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Серія: | Frontiers in Genetics |
Предмети: | |
Онлайн доступ: | http://journal.frontiersin.org/article/10.3389/fgene.2018.00036/full |