Pathological Remodeling of Mitral Valve Leaflets from Unphysiologic Leaflet Mechanics after Undersized Mitral Annuloplasty to Repair Ischemic Mitral Regurgitation

Pathological Remodeling of Mitral Valve Leaflets from Unphysiologic Leaflet Mechanics after Undersized Mitral Annuloplasty to Repair Ischemic Mitral Regurgitation

Background Undersized ring annuloplasty is a commonly used surgical repair for ischemic mitral regurgitation, in which annular downsizing corrects regurgitation, but alters valve geometry and elevates tissue stresses. In this study, we investigated if unphysiological leaflet kinematics after annulop...

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Bibliographic Details
Main Authors: Alicja Sielicka, Eric L. Sarin, Weiwei Shi, Fatiesa Sulejmani, Daniella Corporan, Kanika Kalra, Vinod H. Thourani, Wei Sun, Robert A. Guyton, Muralidhar Padala
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
animal model surgery
mitral valve regurgitation
mitral valve repair, mitral annuloplasty, subannular repair, mitral valve fibrosis, heart valve repair durability, mitral valve
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009777

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.009777

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