Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

Abstract Background The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization. Oocyte maturation is only possible in the presence of surrounding, diverse, and changing layers of somatic ce...

Full description

Bibliographic Details
Main Authors: Beatriz Peñalver Bernabé, Ines Thiele, Eugene Galdones, Anaar Siletz, Sriram Chandrasekaran, Teresa K. Woodruff, Linda J. Broadbelt, Lonnie D. Shea
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Bioinformatics
Subjects:
Ovarian follicle development
Metabolism
Metabolic communities
Secreted metabolites
Cell-type specific metabolic models
Genome-scale modeling
Online Access:http://link.springer.com/article/10.1186/s12859-019-2825-2

Internet

http://link.springer.com/article/10.1186/s12859-019-2825-2

Similar Items