Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats

ABSTRACT Background: Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its neuropsychiatric comorbidities. Objective: To investigate the effects of serotonergic modulation on pro-inflammatory cytokines a...

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Bibliographic Details
Main Authors: Ibrahim Ethem Torun, Yasemin Baranoglu Kılınc, Erkan Kilinc
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2022-01-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022005002203&lng=en&tlng=en