Evaluation of drug repositioning by molecular docking of pharmaceutical resources available in the Brazilian healthcare system against SARS-CoV-2

Evaluation of drug repositioning by molecular docking of pharmaceutical resources available in the Brazilian healthcare system against SARS-CoV-2

In 2020 SARS-CoV-2 reached pandemic status, reaching Brazil in mid-February. As of now, no specific drugs for treating the disease are available. In this work, the possibility of interaction between SARS-CoV-2 viral proteins (open and closed spike protein, isolate spike protein RBD, NSP 10, NSP 16,...

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Bibliographic Details
Main Authors: Matheus V.C. Grahl, Allan M. Alcará, Ana Paula A. Perin, Carlo F. Moro, Éderson S.M. Pinto, Bruno C. Feltes, Isadora M. Ghilardi, Felipe V.F. Rodrigues, Marcio Dorn, Jaderson C. da Costa, Osmar Norberto de Souza, Rodrigo Ligabue-Braun
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Drug repositioning
SUS
SARS-CoV-2
Molecular docking
COVID19
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914821000290

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http://www.sciencedirect.com/science/article/pii/S2352914821000290

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