Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking
Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process. To characterize the ss-tail binding site on M-MuLV integrase, we...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100009 |