Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations

Large organized chromatin lysine (K) domains (LOCKs) are a genomic feature derived from the cluster of modified nucleosomes. Here the authors provide evidence that LOCKs discriminate primitive from differentiated cell populations and that they relate to transcription regulating events.

Bibliographic Details
Main Authors: Seyed Ali Madani Tonekaboni, Benjamin Haibe-Kains, Mathieu Lupien
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20830-9