Role of periostin in inflammatory bowel disease development and synergistic effects mediated by the CCL5–CCR5 axis

Role of periostin in inflammatory bowel disease development and synergistic effects mediated by the CCL5–CCR5 axis

Inflammatory bowel disease (IBD), comprising mainly Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease of the gastrointestinal tract. In recent years, a wealth of data has been accumulated demonstrating the complex interplay of many different factors in the pathogene...

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Bibliographic Details
Main Authors: Saida Mukanova, Anton Borissenko, Alexey Kim, Aigerim Bolatbek, Ainur Abdrakhmanova, Luca Vangelista, Eva Sonnenberg-Riethmacher, Dieter Riethmacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
periostin (POSTN)
CCL5-CCR5-signaling system
IBD – inflammatory bowel disease
inflammation
treatment option
chemically induced colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.956691/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.956691/full

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