Metabolic Responses to Polymyxin Treatment in <italic toggle="yes">Acinetobacter baumannii</italic> ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling
ABSTRACT Multidrug-resistant (MDR) Acinetobacter baumannii has emerged as a very problematic pathogen over the past decades, with a high incidence in nosocomial infections. Discovered in the late 1940s but abandoned in the 1970s, polymyxins (i.e., polymyxin B and colistin) have been revived as the l...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-02-01
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Series: | mSystems |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSystems.00157-18 |