Gα<sub>s</sub>-Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization

Gα<sub>s</sub>-Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization

An inflammatory response following dental pulp injury and/or infection often leads to neurogenic inflammation via the axon reflex. However, the detailed mechanism underlying the occurrence of the axon reflex in the dental pulp remains unclear. We sought to examine the intracellular cyclic adenosine...

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Bibliographic Details
Main Authors: Natsuki Saito, Maki Kimura, Takehito Ouchi, Tatsuya Ichinohe, Yoshiyuki Shibukawa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
axon reflex
cAMP
CGRP
dental pulp
inflammatory response
odontoblasts
Online Access:https://www.mdpi.com/2218-273X/12/12/1747

Internet

https://www.mdpi.com/2218-273X/12/12/1747

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