Titratable residues that drive RND efflux: Insights from molecular simulations
The resistance–nodulation–division efflux machinery confers antimicrobial resistance to Gram-negative bacteria by actively pumping antibiotics out of the cell. The protein complex is powered by proton motive force; however, the proton transfer mechanism itself and indeed even its stoichiometry is st...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2024-01-01
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Series: | QRB Discovery |
Subjects: | |
Online Access: | https://www.cambridge.org/core/product/identifier/S2633289224000061/type/journal_article |