Titratable residues that drive RND efflux: Insights from molecular simulations

The resistance–nodulation–division efflux machinery confers antimicrobial resistance to Gram-negative bacteria by actively pumping antibiotics out of the cell. The protein complex is powered by proton motive force; however, the proton transfer mechanism itself and indeed even its stoichiometry is st...

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Bibliographic Details
Main Authors: Robert Clark, Kahlan E. Newman, Syma Khalid
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:QRB Discovery
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2633289224000061/type/journal_article

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