Bordetella pertussis autotransporter Vag8 binds human C1 esterase inhibitor and confers serum resistance.

Bordetella pertussis employs numerous strategies to evade the immune system, including the ability to resist killing via complement. Previously we have shown that B. pertussis binds a complement regulatory protein, C1 esterase inhibitor (C1inh) to its surface in a Bvg-regulated manner (i.e. during i...

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Bibliographic Details
Main Authors: Nico Marr, Nita R Shah, Rose Lee, Emma J Kim, Rachel C Fernandez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3114845?pdf=render