FOXP3 promoter demethylation reveals the committed Treg population in humans.

FOXP3 promoter demethylation reveals the committed Treg population in humans.

BACKGROUND: Naturally occurring thymus derived regulatory T cells (Tregs) are central in the maintenance of self-tolerance. The transcription factor FOXP3 is crucial for the suppressive activity of Tregs and is considered the most specific marker for this population. However, human non regulatory T...

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Bibliographic Details
Main Authors: Peter C J Janson, Malin E Winerdal, Per Marits, Magnus Thörn, Rolf Ohlsson, Ola Winqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2238816?pdf=render

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http://europepmc.org/articles/PMC2238816?pdf=render

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