Multi-tissue transcriptome-wide association study identifies novel candidate susceptibility genes for cataract

IntroductionCataract is the leading cause of blindness among the elderly worldwide. Twin and family studies support an important role for genetic factors in cataract susceptibility with heritability estimates up to 58%. To date, 55 loci for cataract have been identified by genome-wide association st...

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Bibliographic Details
Main Authors: Hélène Choquet, Matthieu Duot, Victor A. Herrera, Sanjaya K. Shrestha, Travis J. Meyers, Thomas J. Hoffmann, Poorab K. Sangani, Salil A. Lachke
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Ophthalmology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2024.1362350/full