The <i>Anemonia sulcata</i> Toxin BDS-I Protects Astrocytes Exposed to Aβ<sub>1–42</sub> Oligomers by Restoring [Ca<sup>2+</sup>]<sub>i</sub> Transients and ER Ca<sup>2+</sup> Signaling

The <i>Anemonia sulcata</i> Toxin BDS-I Protects Astrocytes Exposed to Aβ<sub>1–42</sub> Oligomers by Restoring [Ca<sup>2+</sup>]<sub>i</sub> Transients and ER Ca<sup>2+</sup> Signaling

Intracellular calcium concentration ([Ca<sup>2+</sup>]<sub>i</sub>) transients in astrocytes represent a highly plastic signaling pathway underlying the communication between neurons and glial cells. However, how this important phenomenon may be compromised in Alzheimer’s dis...

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Bibliographic Details
Main Authors: Ilaria Piccialli, Valentina Tedeschi, Francesca Boscia, Roselia Ciccone, Antonella Casamassa, Valeria de Rosa, Paolo Grieco, Agnese Secondo, Anna Pannaccione
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Toxins
Subjects:
astrocytes
Aβ<sub>1–42</sub> oligomers
BDS-I
[Ca<sup>2+</sup>]<sub>i</sub> transients
ER stress
K<sub>V</sub>3.4 channel
Online Access:https://www.mdpi.com/2072-6651/13/1/20

Internet

https://www.mdpi.com/2072-6651/13/1/20

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