Epigenetic profiling reveals key genes and cis-regulatory networks specific to human parathyroids

Abstract In all terrestrial vertebrates, the parathyroid glands are critical regulators of calcium homeostasis and the sole source of parathyroid hormone (PTH). Hyperparathyroidism and hypoparathyroidism are clinically important disorders affecting multiple organs. However, our knowledge regarding r...

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Bibliographic Details
Main Authors: Youngsook Lucy Jung, Wenping Zhao, Ian Li, Dhawal Jain, Charles B. Epstein, Bradley E. Bernstein, Sareh Parangi, Richard Sherwood, Cassianne Robinson-Cohen, Yi-Hsiang Hsu, Peter J. Park, Michael Mannstadt
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46181-3