Immunopathology and Trypanosoma congolense parasite sequestration cause acute cerebral trypanosomiasis

Trypanosoma congolense causes a syndrome of variable severity in animals in Africa. Cerebral trypanosomiasis is a severe form, but the mechanism underlying this severity remains unknown. We developed a mouse model of acute cerebral trypanosomiasis and characterized the cellular, behavioral, and phys...

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Bibliographic Details
Main Authors: Sara Silva Pereira, Mariana De Niz, Karine Serre, Marie Ouarné, Joana E Coelho, Cláudio A Franco, Luisa M Figueiredo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/77440