miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1

miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1

Uncontrolled proliferation, migration and phenotypic switching of vascular smooth muscle cells (VSMCs) are important steps in the development and progression of aortic dissection (AD). The function and potential mechanism of miR-335-5p in the pathogenesis of AD are explored in this study. Specifical...

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Bibliographic Details
Main Authors: Ma Runwei, Zhang Dayong, Song Yi, Kong Jichang, Mu Chunjie, Shen Pin, Gui Wenting
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-07-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
aortic dissection
miR-335-5p
phenotypic switch
vascular smooth muscle cells
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022081

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022081

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