Commentary on the role of treatment-related HIV compensatory mutations on increasing virulence: new discoveries twenty years since the clinical testing of protease inhibitors to block HIV-1 replication
<p>Abstract</p> <p>Approximately 20 years has passed since the first human trial with HIV-1 protease inhibitors. Protease inhibitors set the stage for combination therapy in the mid-1990s but are now rarely used in first-line combination therapy and reserved for salvage therapy. In...
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| Format: | Article |
| Language: | English |
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BMC
2012-10-01
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| Series: | BMC Medicine |
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| Online Access: | http://www.biomedcentral.com/1741-7015/10/114 |