Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development
Retinoic acid (RA) is a diffusible molecule involved in early forebrain patterning. Its later production in the meninges by the retinaldehyde dehydrogenase RALDH2 coincides with the time of cortical neuron generation. A function of RA in this process has not been adressed directly as Raldh2−/− mouse...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-02-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/6/2/148 |