Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathway

Hypoxia induces docetaxel resistance in triple-negative breast cancer via the HIF-1α/miR-494/Survivin signaling pathway

Cytotoxic chemotherapy is the major strategy to prevent and reduce triple-negative breast cancer (TNBC) progression and metastasis. Hypoxia increases chemoresistance and is associated with a poor prognosis for patients with cancer. Based on accumulating evidence, microRNAs (miRNAs) play an important...

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Bibliographic Details
Main Authors: Hongchang Li, Xianhao Sun, Jindong Li, Weiyan Liu, Gaofeng Pan, Anwei Mao, Jiazhe Liu, Qing Zhang, Longhua Rao, Xiaofeng Xie, Xia Sheng
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
miR-494
HIF-1α
Survivin
TNBC
Drug-resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622000483

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http://www.sciencedirect.com/science/article/pii/S1476558622000483

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