In Vivo Evaluation of Gamma-Irradiated and Heparin-Immobilized Small-Diameter Polycaprolactone Vascular Grafts with VEGF in Aged Rats

In Vivo Evaluation of Gamma-Irradiated and Heparin-Immobilized Small-Diameter Polycaprolactone Vascular Grafts with VEGF in Aged Rats

The effectiveness of small-diameter vascular grafts depends on their antithrombogenic properties and ability to undergo accelerated endothelialization. The extreme hydrophobic nature of poly(ε-caprolactone) (PCL) hinders vascular tissue integration, limiting its use in medical implants. To enhance t...

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Bibliographic Details
Main Authors: Se-Eun Kim, Sung-In Jeong, Kyung-Mi Shim, Kwangsik Jang, Jong-Seok Park, Youn-Mook Lim, Seong-Soo Kang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Polymers
Subjects:
small-diameter vascular graft
polycaprolactone
gamma irradiation
heparin
VEGF
aged rat
Online Access:https://www.mdpi.com/2073-4360/14/6/1265

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https://www.mdpi.com/2073-4360/14/6/1265

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