Polymeric nature of tandemly repeated genes enhances assembly of constitutive heterochromatin in fission yeast

Abstract Motivated by our recent experiments that demonstrate that the tandemly repeated genes become heterochromatin, here we show a theory of heterochromatin assembly by taking into account the connectivity of these genes along the chromatin in the kinetic equations of small RNA production and his...

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Bibliographic Details
Main Authors: Tetsuya Yamamoto, Takahiro Asanuma, Yota Murakami
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05154-w