Methionine sulfoxide reductases are essential for virulence of Salmonella typhimurium.

Production of reactive oxygen species represents a fundamental innate defense against microbes in a diversity of host organisms. Oxidative stress, amongst others, converts peptidyl and free methionine to a mixture of methionine-S- (Met-S-SO) and methionine-R-sulfoxides (Met-R-SO). To cope with such...

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Bibliographic Details
Main Authors: Luisa A Denkel, Sarah A Horst, Syed Fazle Rouf, Vera Kitowski, Oliver M Böhm, Mikael Rhen, Timo Jäger, Franz-Christoph Bange
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206869?pdf=render