Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell.

In patients with Parkinson's disease (PD), stem cells can serve as therapeutic agents to restore or regenerate injured nervous system. Here, we differentiated two types of stem cells; mouse embryonic stem cells (mESCs) and protein-based iPS cells (P-iPSCs) generated by non-viral methods, into m...

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Bibliographic Details
Main Authors: Yoo-Wook Kwon, Yeon-Ju Chung, Joonoh Kim, Ho-Jae Lee, Jihwan Park, Tae-Young Roh, Hyun-Jai Cho, Chang-Hwan Yoon, Bon-Kwon Koo, Hyo-Soo Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899054?pdf=render