Alterations in Tau Protein Level and Phosphorylation State in the Brain of the Autistic-Like Rats Induced by Prenatal Exposure to Valproic Acid

Alterations in Tau Protein Level and Phosphorylation State in the Brain of the Autistic-Like Rats Induced by Prenatal Exposure to Valproic Acid

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficient social interaction and communication besides repetitive, stereotyped behaviours. A characteristic feature of ASD is altered dendritic spine density and morphology associated with synaptic plasticity disturban...

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Bibliographic Details
Main Authors: Magdalena Gąssowska-Dobrowolska, Agnieszka Kolasa-Wołosiuk, Magdalena Cieślik, Agnieszka Dominiak, Kristina Friedland, Agata Adamczyk
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
α/β-tubulin
MAP-Tau
GSK-3β
CDK5
ERK1/2
Akt/mTOR signalling
Online Access:https://www.mdpi.com/1422-0067/22/6/3209

Internet

https://www.mdpi.com/1422-0067/22/6/3209

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