Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis

Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis

Herein, we report the synthesis of a biomimic hydrogel adhesive that addresses the poor healing of surgical anastomosis. Dopamine-conjugated xanthan gum (Da-g-Xan) is fabricated using deep insights into the molecular similarity between mussels' adhesive and dopamine as well as the structural si...

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Bibliographic Details
Main Authors: Jinjian Huang, Yungang Jiang, Ye Liu, Yanhan Ren, Ziyan Xu, Zongan Li, Yun Zhao, Xiuwen Wu, Jianan Ren
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-03-01
Series:Bioactive Materials
Subjects:
Marine animals
Non-covalent hydrogel
Xanthan gum
Mannose receptors
Surgical anastomosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20302292

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http://www.sciencedirect.com/science/article/pii/S2452199X20302292

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