Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1

Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1

Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are attributed to oxidative stress, endoplasmic reticulum (ER) activation and infl...

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Bibliographic Details
Main Authors: Hatem Maamoun, Tarek Benameur, Gianfranco Pintus, Shankar Munusamy, Abdelali Agouni
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
heme oxygenase-1 (Ho-1)
endothelial dysfunction
angiogenesis
oxidative stress
ER stress
diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00070/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00070/full

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