Utilizing GCaMP transgenic mice to monitor endogenous Gq/11 coupled receptors
The family of GCaMPs are engineered proteins that contain Ca2+ binding motifs within a circularly permutated variant of Aequorea Victoria green fluorescent protein (cp-GFP). The rapidly advancing field of utilizing GCaMP reporter constructs represents a major step forward in our ability to monitor i...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2015-03-01
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Series: | Frontiers in Pharmacology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00042/full |