Utilizing GCaMP transgenic mice to monitor endogenous Gq/11 coupled receptors

The family of GCaMPs are engineered proteins that contain Ca2+ binding motifs within a circularly permutated variant of Aequorea Victoria green fluorescent protein (cp-GFP). The rapidly advancing field of utilizing GCaMP reporter constructs represents a major step forward in our ability to monitor i...

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Bibliographic Details
Main Author: John G Partridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00042/full