In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles

Nanoparticle-based drug delivery systems have the potential to revolutionize medicine, but their low vascular permeability and rapid clearance by phagocytic cells have limited their medical impact. Nanoparticles delivered at the in utero stage can overcome these key limitations due to the high rate...

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Bibliographic Details
Main Authors: Kewa Gao, Jie Li, Hengyue Song, Hesong Han, Yongheng Wang, Boyan Yin, Diana L. Farmer, Niren Murthy, Aijun Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2300049X