Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

<p>Abstract</p> <p>Background</p> <p>Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the present study, we aim to t...

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Détails bibliographiques
Auteurs principaux: Jiang Hong, Badralmaa Yunden, Yang Jun, Lempicki Richard, Hazen Allison, Natarajan Ven
Format: Article
Langue:English
Publié: BMC 2012-07-01
Collection:Lipids in Health and Disease
Sujets:
ABCA1
ATRA
retinoic acid
TO-901317
RAR
RXR
LXR
cholesterol efflux
HIV-1
CD4+ T cells
Accès en ligne:http://www.lipidworld.com/content/11/1/69

Internet

http://www.lipidworld.com/content/11/1/69

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