Wounding promotes ovarian cancer progression and decreases efficacy of cisplatin in a syngeneic mouse model

Wounding promotes ovarian cancer progression and decreases efficacy of cisplatin in a syngeneic mouse model

Abstract Background Primary cytoreductive surgery followed by adjuvant chemotherapy is the standard treatment for advanced epithelial ovarian cancer. The average interval between surgery and chemotherapy initiation is approximately 4-weeks at most centers; however, since surgery may accelerate resid...

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Bibliographic Details
Main Authors: Yooyoung Lee, Alexandra Kollara, Taymaa May, Theodore J. Brown
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
ID8 cells
Wound healing
Cisplatin
Mouse
Chemoresistance
Online Access:http://link.springer.com/article/10.1186/s13048-018-0428-6

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http://link.springer.com/article/10.1186/s13048-018-0428-6

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