Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

Abstract Background Oxidative stress induces various intracellular damage, which might be correlated with tumorigenesis. Accumulated oxidative stresses might inactivate protein tyrosine phosphatase (PTP) by oxidizing it, and inducing the phosphorylation of H2AX (γH2AX) in response to DNA damage. Met...

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Bibliographic Details
Main Authors: Usama Khamis Hussein, Ho Sung Park, Jun Sang Bae, Kyoung Min Kim, Yun Jo Chong, Chan Young Kim, Keun Sang Kwon, Myoung Ja Chung, Ho Lee, Myoung Jae Kang, Woo Sung Moon, Kyu Yun Jang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Stomach
Carcinoma
Oxidative stress
Protein tyrosine phosphatase
γH2AX
Online Access:http://link.springer.com/article/10.1186/s12885-018-4752-4

Internet

http://link.springer.com/article/10.1186/s12885-018-4752-4

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