Mechanistic role of mesencephalic astrocyte-derived neurotrophic factor in myocardial ischemia/reperfusion injury

Abstract Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a protein crucial for cellular stress response and survival, particularly in the nervous and cardiovascular systems. Unlike traditional neurotrophic factors, MANF primarily regulates endoplasmic reticulum (ER) stress and protects...

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Bibliographic Details
Main Authors: Fahimeh Varzideh, Brandon Wang, Yifei Qin, Urna Kansakar, Gaetano Santulli, Stanislovas S. Jankauskas
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Molecular Medicine
Online Access:https://doi.org/10.1186/s10020-024-00927-3