Widespread distribution of a newly found point mutation in voltage-gated sodium channel in pyrethroid-resistant Aedes aegypti populations in Vietnam.

BACKGROUND:Resistance of Aedes aegypti to photostable pyrethroid insecticides is a major problem for disease-vector control programs. Pyrethroids target the voltage-gated sodium channel on the insects' neurons. Single amino acid substitutions in this channel associated with pyrethroid resistanc...

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Bibliographic Details
Main Authors: Hitoshi Kawada, Yukiko Higa, Osamu Komagata, Shinji Kasai, Takashi Tomita, Nguyen Thi Yen, Luu Lee Loan, Rodrigo A P Sánchez, Masahiro Takagi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2754656?pdf=render