PTEN inhibitor improves vascular remodeling and cardiac function after myocardial infarction through PI3k/Akt/VEGF signaling pathway

PTEN inhibitor improves vascular remodeling and cardiac function after myocardial infarction through PI3k/Akt/VEGF signaling pathway

Abstract Background Myocardial infarction (MI) is the leading cause of death from cardiovascular disease (CVD). Currently, the efficacy for MI treatment remains unsatisfactory. Therefore, it is urgent to develop a novel therapeutic strategy. Methods Left anterior descending arteries (LAD) of mice we...

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Bibliographic Details
Main Authors: Qiuting Feng, Xing Li, Xian Qin, Cheng Yu, Yan Jin, Xiaojun Qian
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Medicine
Subjects:
PTEN inhibitor
Angiogenesis
Cardiac function
PI3K
Akt
VEGF
Online Access:http://link.springer.com/article/10.1186/s10020-020-00241-8

Internet

http://link.springer.com/article/10.1186/s10020-020-00241-8

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