Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart

Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart

Cardiovascular complications are common in type 1 diabetes mellitus (TIDM) and there is an increased risk of arrhythmias as a result of dysfunction of the cardiac conduction system (CCS). We have previously shown that, in vivo, there is a decrease in the heart rate and prolongation of the QRS comple...

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Bibliographic Details
Main Authors: Yu Zhang, Yanwen Wang, Joseph Yanni, Mohammed Anwar Qureshi, Sunil Jit R. J. Logantha, Sarah Kassab, Mark R. Boyett, Natalie J. Gardiner, Hong Sun, Frank Christopher Howarth, Halina Dobrzynski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Physiology
Subjects:
type I diabetes
arrhythmias
cardiac conduction system
ion channels
calcium handling protein
gap junction channels
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00826/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.00826/full

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