Artichoke (Cynara Scolymus) Methanolic Leaf Extract Alleviates Diethylnitrosamine-Induced Toxicity in BALB/c Mouse Brain: Involvement of Oxidative Stress and Apoptotically Related Klotho/PPARγ Signaling

Artichoke (Cynara Scolymus) Methanolic Leaf Extract Alleviates Diethylnitrosamine-Induced Toxicity in BALB/c Mouse Brain: Involvement of Oxidative Stress and Apoptotically Related Klotho/PPARγ Signaling

(1) Background: Various epidemiological studies suggest that oxidative stress and disrupted neuronal function are mechanistically linked to neurodegenerative diseases (NDs), including Parkinson’s disease (PD) and Alzheimer’s disease (AD). DNA damage, oxidative stress, lipid peroxidation, and eventua...

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Bibliographic Details
Main Authors: Betul Cicek, Sidika Genc, Yesim Yeni, Mehmet Kuzucu, Ahmet Cetin, Serkan Yildirim, Ismail Bolat, Mecit Kantarci, Ahmet Hacimuftuoglu, Georgios Lazopoulos, Aristidis Tsatsakis, Konstantinos Tsarouhas, Ali Taghizadehghalehjoughi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Personalized Medicine
Subjects:
DEN
artichoke
oxidative stress
apoptosis
Klotho
PPARγ
Online Access:https://www.mdpi.com/2075-4426/12/12/2012

Internet

https://www.mdpi.com/2075-4426/12/12/2012

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