Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

Summary: The nuclear cap-binding complex (CBC) coordinates co-transcriptional maturation, transport, or degradation of nascent RNA polymerase II (Pol II) transcripts. CBC with its partner ARS2 forms mutually exclusive complexes with diverse “effectors” that promote either productive or destructive o...

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Bibliographic Details
Main Authors: Etienne Dubiez, Erika Pellegrini, Maja Finderup Brask, William Garland, Anne-Emmanuelle Foucher, Karine Huard, Torben Heick Jensen, Stephen Cusack, Jan Kadlec
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016509

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http://www.sciencedirect.com/science/article/pii/S2211124723016509

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