Methylene tetrahydrofolate reductase A1298C polymorphisms influence the adult sequelae of chemotherapy in childhood-leukemia survivors.

This retrospective correlation study investigated the putative link between methylene tetrahydrofolate reductase (MTHFR) A1298C mutations and chemotherapy-related brain function changes in adult childhood-leukemia survivors. To this end, we determined the relationship between the particular MTHFR129...

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Bibliographic Details
Main Authors: Iris Elens, Sabine Deprez, Thibo Billiet, Charlotte Sleurs, Veerle Labarque, Anne Uyttebroeck, Stefaan Van Gool, Jurgen Lemiere, Rudi D'Hooge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0250228&type=printable