Systematic analysis of MCM3 in pediatric medulloblastoma via multi-omics analysis

Systematic analysis of MCM3 in pediatric medulloblastoma via multi-omics analysis

Minichromosome maintenance proteins are DNA-dependent ATPases that bind to replication origins and allow a single round of DNA replication. One member of this family, MCM3, is reportedly active in most cancers. To systematically elucidate the mechanisms affected by aberrant MCM3 expression and evalu...

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Bibliographic Details
Main Authors: Liangliang Cao, Yang Zhao, Zhuangzhuang Liang, Jian Yang, Jiajia Wang, Shuaiwei Tian, Qinhua Wang, Baocheng Wang, Heng Zhao, Feng Jiang, Jie Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
MCM3
medulloblastoma
multi-omics
DNA methylation
single cell
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.815260/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.815260/full

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