Utilizing experimental design and desirability function in optimizing RP-HPLC method for simultaneous determination of some skeletal muscle relaxants and analgesics
Abstract An experimental design and response surface methodologies using Plackett–Burman and Box-Behnken designs were applied for selecting and optimizing the most appropriate parameters which significantly affect the separation and quantitative estimation of five skeletal muscle relaxants and four...
Hlavní autoři: | , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Nature Portfolio
2024-05-01
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Edice: | Scientific Reports |
Témata: | |
On-line přístup: | https://doi.org/10.1038/s41598-024-58381-4 |