The Genes–Stemness–Secretome Interplay in Malignant Pleural Mesothelioma: Molecular Dynamics and Clinical Hints

The Genes–Stemness–Secretome Interplay in Malignant Pleural Mesothelioma: Molecular Dynamics and Clinical Hints

MPM has a uniquely poor somatic mutational landscape, mainly driven by environmental selective pressure. This feature has dramatically limited the development of effective treatment. However, genomic events are known to be associated with MPM progression, and specific genetic signatures emerge from...

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Bibliographic Details
Main Authors: Giulia M. Stella, Caterina Marchiò, Elia Bari, Ilaria Ferrarotti, Francesco R. Bertuccio, Antonella Di Gennaro, David Michael Abbott, Paola Putignano, Ilaria Campo, Maria Luisa Torre, Angelo G. Corsico
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
malignant pleural mesothelioma
genetics
microenvironment
targeted therapies
Online Access:https://www.mdpi.com/1422-0067/24/4/3496

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https://www.mdpi.com/1422-0067/24/4/3496

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