Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids.

Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids.

Meiotic mapping of quantitative trait loci regulating expression (eQTLs) has allowed the construction of gene networks. However, the limited mapping resolution of these studies has meant that genotype data are largely ignored, leading to undirected networks that fail to capture regulatory hierarchie...

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Bibliographic Details
Main Authors: Sangtae Ahn, Richard T Wang, Christopher C Park, Andy Lin, Richard M Leahy, Kenneth Lange, Desmond J Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2690838?pdf=render

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http://europepmc.org/articles/PMC2690838?pdf=render

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