Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms
<p>Abstract</p> <p>Background</p> <p>Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both gene repression and activation. To eliminate indirect effects and examine the direct consequences of Dot1 binding...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2011-02-01
|
Series: | Epigenetics & Chromatin |
Online Access: | http://www.epigeneticsandchromatin.com/content/4/1/2 |