Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma

Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma

Summary: Chromatin dysregulation has emerged as an important mechanism of oncogenesis. To develop targeted treatments, it is important to understand the transcriptomic consequences of mutations in chromatin modifier genes. Recently, mutations in the histone methyltransferase gene nuclear receptor bi...

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Bibliographic Details
Main Authors: Nargess Farhangdoost, Cynthia Horth, Bo Hu, Eric Bareke, Xiao Chen, Yinglu Li, Mariel Coradin, Benjamin A. Garcia, Chao Lu, Jacek Majewski
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Cell Reports
Subjects:
histone H3 lysine 36 dimethylation
nuclear receptor binding SET domain protein 1
histone modifications
epigenomics
head and neck squamous cell carcinoma
cis-regulatory elements
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721000826

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http://www.sciencedirect.com/science/article/pii/S2211124721000826

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