Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.

Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.

The mammalian target of rapamycin (mTOR) modulates immune responses and cellular proliferation. The objective of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house dust mite (HDM)-induced asthma. In an induction mod...

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Bibliographic Details
Main Authors: Karin Fredriksson, Jill A Fielhaber, Jonathan K Lam, Xianglan Yao, Katharine S Meyer, Karen J Keeran, Gayle J Zywicke, Xuan Qu, Zu-Xi Yu, Joel Moss, Arnold S Kristof, Stewart J Levine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368343?pdf=render

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http://europepmc.org/articles/PMC3368343?pdf=render

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